Review of potential predictors of anthracycline-induced cardiotoxicity from the position of disease pathogenesis

Cardiotoxicity of anthracycline chemotherapy drugs is one the main interdisciplinary problems in research area cardio-oncology. As known, high antitumor efficacy antibiotics significantly leveled by development disabling and lethal heart lesions. However, pathogenesis toxic disease, as well diagnostic criteria markers anthracycline-induced cardiomyopathy are not fully understood. The article provides a detailed review potential cardiotoxicity from position disease pathogenesis. scheme pathogenetic proposed this article. methods diagnostics damage that currently used clinical researches domestic foreign scientists reviewed.